PP_000VLWW.2

Germany/PP_000VLWW.2/2022-09
A. Brinkmann, C. Kohl, K. Pape, D. Bourquain, A. Thurmer, J. Michel, L. Schaade & A. Nitsche

Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses

Sample details

Collection date
2022-09
Sampling location
Germany
Isolate name
MPXV/Germany/2022/RKI339

Data use terms

Data use terms
OPEN

Data use terms history

ChangedUserData use terms
2024-12-09 18:48insdc_ingest_userOPEN
Data use terms URL

Clade & Lineage

Clade
IIb
Outbreak
sh2017
Lineage
B.1

INSDC

INSDC accession
NCBI release date
2022-10-21
NCBI update date
2022-10-21
Raw reads accession

Host

Host

Submission details

Submission ID
OP696842.1
Submitting group
Date submitted
2025-02-03 15:01:44 UTC
Date released
2025-02-03 15:09:28 UTC
Earliest release date
2022-10-21

Alignment and QC

Length
208626 (100%)
# of SNPs
1692
# of inserted bases
11644
# of deleted bases
227
# of frame shifts
76
# of stop codons
1
Frame shifts
OPG019:3-8(nt:7586-7602),OPG019:18-33(nt:7631-7678),OPG019:36-42(nt:7683-7705),OPG019:45-87(nt:7712-7840),OPG019:90-93(nt:7847-7858),OPG019:97-103(nt:7868-7887),OPG019:114(nt:7917-7921),OPG019:118-135(nt:7930-7984),OPG019:142-143(nt:8003-8008),OPG021:6-9(nt:9602-9612),OPG021:11-15(nt:9617-9631),OPG021:35-54(nt:9689-9748),OPG021:61-65(nt:9767-9781),OPG021:72-74(nt:9800-9808),...
Stop Codons
OPG021:195

Nucleotide mutations

Mutations called relative to the NC_063383.1 reference

Substitutions

  • G1262A
  • G2591A
  • G3111A
  • G3522A
  • C3818T
  • C6423A
  • C6429G
  • T6430C
  • C6433A
  • C6439A
  • A6448T
  • C6453A
  • A6475T
  • A6481G
  • C6483A
  • C6486G
  • A6494G
  • A6496G
Deletions

607-609, 6593, 6679, 6703-6706, 6745-6749, 6788, 6986, 6987, 7012-7016, 7208-7211, 7248-7254, 7447, 7448, 7585, 7592, 7603, 7649, 7829, 7916, 7985, 8140-8142, 8176, 8177, 8201, 8443-8445, 8519, 8552, 8637, 8638, 8985, 9094, 9159-9163, 9337-9344, 9711, 9782, 9783, 9799, 10025-10029, 10064, 10625, 10676-10681, 10688, 11354, 11617-11621, 11714, 11740, 11776-11781, 12043, 12044, 12137,...
Insertions

ins_6423:ATTTCAGTATAT, ins_6431:GTTATAAAAGTAATGTTGTTTAATTGTAGGACGGTTGTTAGTA, ins_6437:CATGAATAATAATATTCTAATTCCTCGTATTGAC, ins_6443:CAGATACTCGAAATAGTCTGAAAAATTCTTCAAAGA, ins_6454:AGATCTAGGAAAAGT, ins_6460:CCGACCATGAACGAGATAGATGGATAAATATCCTTTCCATCAAAGG, ins_6465:ATTGGATAATT, ins_6468:CAGCAATATATCTGCTG, ins_6473:GTTAT, ins_6478:TTCCATTTATTTTCAGATTG, ins_6489:TA,...

Amino acid substitutions

Substitutions called relative to the NC_063383.1 reference

Substitutions

OPG001

  • OPG001:S105L

OPG002

  • OPG002:S54F

OPG003

  • OPG003:D264N

OPG021

  • OPG021:D195*
  • OPG021:N198I
  • OPG021:R214S

OPG025

  • OPG025:A423D

OPG034

  • OPG034:R111K

OPG047

  • OPG047:R48C

OPG053

  • OPG053:P78S

OPG056

  • OPG056:E125K

OPG057

  • OPG057:E353K

OPG071

  • OPG071:L108F

OPG072

  • OPG072:D56N

OPG092

  • OPG092:D196N

OPG093

  • OPG093:S30L
  • OPG093:D88N

OPG094

  • OPG094:M142I

OPG098

  • OPG098:E162K

OPG105

  • OPG105:S734L

OPG109

  • OPG109:H740Y

OPG118

  • OPG118:K606E

OPG136

  • OPG136:D98N

OPG139

  • OPG139:A17T

OPG145

  • OPG145:E62K
  • OPG145:R243Q
  • OPG145:E435K

OPG150

  • OPG150:S307L

OPG156

  • OPG156:E119K

OPG176

  • OPG176:H221Y

OPG193

  • OPG193:L263F

OPG210

  • OPG210:D209N
  • OPG210:P722S
  • OPG210:M1741I
Deletions

OPG019

OPG019:113, OPG019:136

OPG021

OPG021:66, OPG021:147, OPG021:148, OPG021:160

OPG023

OPG023:141, OPG023:142, OPG023:428

OPG024

OPG024:46-49
Insertions

OPG019

ins_OPG019:9:DDLISFTIICGI*STXXXXXXXXXXXXXXXXXXXXXXXXXYIEIRETVS, ins_OPG019:40:RLILHCVX, ins_OPG019:106:Y*TXXXXXILNNLARXXXXXXXIKHL*IILT*HSFS*LIQYLEDXXGKYSNTC, ins_OPG019:143:VLKELNYFISTXX

OPG021

ins_OPG021:0:IVLTLLFDRXXXXXADVGRGVVTGAYVGX, ins_OPG021:8:TVL*SIV*LYIEGSYVVIGVTVGSSSV, ins_OPG021:35:XTPSAISVQLNVANNLLRSLCLTTXXXXXGSDATXXXLSSTCSN*MSXXXAVFLIHVS*HHEHVTVRYIA, ins_OPG021:55:LYIQFIEQNN*AQ*RNSA**LCFFSY, ins_OPG021:96:EYKEYTNQ*STIDPITIVCRQPPIREV, ins_OPG021:106:FISHCYINGF*TVSS, ins_OPG021:116:XXSHFTHG*KSK*CRRLLTFYRNT*N, ins_OPG021:131:CTTYSKP*PISYISQWYVQTIRXXXYVDSPVFGTDSVVIE...

OPG022

ins_OPG022:0:ISXXXXXXXXXXXCNHNYRRCR, ins_OPG022:56:XXXXXXXXXXXXXXXXXXXXXXQWVMISRRCYPIYP*HYLVMACVY*INXXXXXXXXXXXXXXXXXXXXXXDMEEDTNIS, ins_OPG022:127:XXXXXXXXQYHNDVTLL*SVYVTRYI*CAYGTYI*KHLLTIFYACIINGM*YDLIDCVHDTNLSSMNTEYKHKLKFNIIYLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIVIVWSMPWISLKN*S*NIRMKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRIHPMIRRMTIMTWT*IFR

OPG023

ins_OPG023:1:SLXXXXVSVSESNIDLISYPQIVNERSTGKMVCPNINAFXXXXXXXXXXXXDIDALEIRXXXXXXXXXXXXXXXXXXXXXXXXVF*NIYIYIYIYIYIYIYIYIYIWAKHITXXXXXXXXXGIE*YLLL*XXXXXXXXXXXXX*LLHVEYR, ins_OPG023:45:YYILVKH*SX, ins_OPG023:95:NN*RTYCY, ins_OPG023:143:LILDXXXXXYF*KITTSXXXXXXXXXXXXXXXXXXXXXXXXXKGGMRYIDLCSFKTYANFEEFXXXISRDIAL, ins_OPG023:191:GGVYTYKNIIKMXXXXXXXXXXXXXXXXXXXXXXXXXLTINDLYNI*YPPTKV*LYFSHVMCVKN*...

OPG024

ins_OPG024:35:SLRCSITWIIPSYSGVXXXXXXXXX

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