PP_004JWJU.1

Display Name: South_Africa/PP_004JWJU.1/2025-09-30
J. Maritz, D. Goedhals, J. Pekeur, T. Maponga, M. Claassen, T. Stander, G. van Zyl, W. Preiser, L. M. Hofstra, L. Chabuka, K. W. Liedeman, S. De Villiers, V. Wentzel, L. Singh, T. Ramakutoane, H. Tegally, E. Wilkinson & T. de Oliveira

Sample details

Collection date
2025-09-30
Sample received date
2025-10-01
Country
South Africa
Admin level 1
Eastern Cape
Admin level 2
Kariega (Uitenhage)
City
Kariega (Uitenhage)
Site
Kariega (Uitenhage)

Data use terms

Data use terms
OPEN

Data use terms history

ChangedUserData use terms
2026-02-13 05:35stepfandvOPEN
Data use terms URL

Lineage

Lineage
B1

Authors

Author affiliations
Centre for Epidemic Response and Innovation (CERI), BMRI building, Tygerberg, Stellenbosch University, Francie Van Zjil Drive, Cape Town, South Africa; PathCare Molecular Lab, PathCare Reference Laboratory, Neels Bothma Street, 7460, Cape Town, South Africa

INSDC

INSDC accession
BioProject accession
BioSample accession
GCA accession

Sampling

Sample type
Swab

Host

Host name - scientific
Homo sapiens
Host name - common
Human
Host age bin
2 - 3
Host gender
M
Host origin country
South Africa

Sequencing

Purpose of sequencing
Surveillance
Sequencing instrument
Illumina NextSeq
Sequencing assay type
WGS
Sequenced by - organization
Centre for Epidemic Response and Innovation (CERI), BMRI building, Tygerberg, Stellenbosch University, Francie Van Zjil Drive, Cape Town, South Africa
Sequenced by - contact name
Stepfan de Villiers
Sequenced by - contact email
stepfan@sun.ac.za
Reference genome accession
NC_039199.1
Consensus sequence software name
Genome Detective
Consensus sequence software version
Pan-viral (2.21.4)
Depth of coverage
893
Breadth of coverage
93

Alignment and QC metrics

Length
13004
Completeness
92.86%
# of SNPs
2182
# of inserted bases
26
# of deleted bases
80
# of ambiguous bases
0
# of unknown bases
661
# of frame shifts
2
# of stop codons
0
Frame shifts
G:149-160(nt:6689-6725),G:216-237(nt:6890-6957)

Submission details

Submission ID
hMPV/B/SouthAfrica/PATH-CERI-C071077/2025
Submitting group
Date submitted
2026-02-13 05:35:59 UTC
Date released
2026-02-13 05:36:07 UTC
Earliest release date
2026-02-13

Nucleotide mutations

Mutations called relative to the NC_039199.1 reference

Substitutions

  • G34A
  • G36A
  • G63A
  • T70C
  • A72G
  • G81A
  • G105A
  • G126A
  • T129C
  • C150T
  • G177T
  • G195T
  • T198C
  • G199A
  • T207C
  • G208A
  • A228T
  • A231G
    • Deletions
    3009, 4684-4722, 6196, 6210-6215, 6688, 6889, 6981-6983, 6990-7009, 7041-7044, 7144-7147
    Insertions
    ins_6696:GAA, ins_6725:GGGGAAGAGGAAAAGA, ins_6945:AT, ins_6965:CC, ins_7060:AG, ins_7073:G

    Amino acid mutations

    Mutations called relative to the NC_039199.1 reference

    Substitutions

    F

  • F:V6M
  • F:F9I
  • F:A61T
  • F:R82K
  • F:V122I
  • F:T135N
  • F:N139G
  • F:K143Q
  • F:D167E
  • F:R175S
  • F:K179R
  • F:N233Y
  • F:F258I
  • F:V286I
  • F:G294E
  • F:K296N
  • F:Q312K
  • F:K348R

    • G

  • G:K4R
  • G:T10A
  • G:L14F
  • G:R17K
  • G:V18I
  • G:V22I
  • G:A23R
  • G:R24S
  • G:K26R
  • G:F28Y
  • G:K29R
  • G:N30Y
  • G:S32T
  • G:V34I
  • G:I38L
  • G:I43M
  • G:Y48F
  • G:I50V

    • L

  • L:L4F
  • L:N5C
  • L:I50V
  • L:I55V
  • L:K61R
  • L:N65M
  • L:S66T
  • L:I75V
  • L:V89M
  • L:T109S
  • L:I115M
  • L:S141V
  • L:K162R
  • L:V182I
  • L:I189V
  • L:S228N
  • L:E231K
  • L:I245M

    • M

  • M:I23V
  • M:E103D
  • M:E111D
  • M:T156I
  • M:K237R
  • M:T241S

    • M2-1

  • M2-1:A5T
  • M2-1:E20D
  • M2-1:I37L
  • M2-1:R52K
  • M2-1:S88G
  • M2-1:V108T
  • M2-1:V130I
  • M2-1:R149K
  • M2-1:K160R
  • M2-1:A169T
  • M2-1:E170D
  • M2-1:S173P

    • M2-2

  • M2-2:E18K
  • M2-2:V22K
  • M2-2:V28S
  • M2-2:D37E
  • M2-2:A41T
  • M2-2:N55S
  • M2-2:A68T

    • N

  • N:A54T
  • N:A57T
  • N:I67M
  • N:S71C
  • N:R96K
  • N:I103G
  • N:N106S
  • N:D110E
  • N:A136V
  • N:M201V
  • N:D212E
  • N:H220Y
  • N:M258L
  • N:A280S
  • N:K356R
  • N:V385M
  • N:D387G
  • N:S389N
  • N:N391D

    • P

  • P:L19I
  • P:R28K
  • P:P30S
  • P:S35T
  • P:I39V
  • P:V46I
  • P:R57K
  • P:K60R
  • P:P61S
  • P:T62S
  • P:I63T
  • P:P64L
  • P:S65L
  • P:T72A
  • P:K74N
  • P:G75S
  • P:A77T
  • P:T80I

    • SH

  • SH:I2K
    • Deletions
    G:148, G:215
    Insertions
    ins_G:143:ITQT, ins_G:189:TT

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