Switzerland/PP_002XJN8.1/2022-12
Rainer Gosert, Karoline Leuzinger, Alexander Kuznetsov & Richard Neher

Clinical Virology, Laboratory Medicine, University Hospital Basel, Basel, Switzerland; Clinical Virology, Laboratory Medicine, University Hospital Basel, Basel, Switzerland, Transplantation and Clinical Virology, Department of Biomedicine, University of Basel, Basel, Switzerland; Biozentrum, University of Basel, Basel, Switzerland

Sample details

Collection date
2022-12
Latitude
47.56065954497
Longitude
7.58504484478
Sampling location
Switzerland (Basel-Stadt)
City
Basel

Data use terms

Data use terms
OPEN

Lineage

Lineage
B.D.E.1

INSDC

INSDC accession
BioProject accession
BioSample accession
GCA accession

Host

Host role
Patient [OMRSE:00000030]
Host vaccination status
Not Vaccinated [GENEPIO:0100102]
Is lab host
False

Sequencing

Amplicon PCR primer scheme
500 bp primers were designed using PRIMAL tool. Additionally, 2000bp-NAT primers and 1000bp-RSV-A and RSV-B subgroup-specific NAT primers were used from Wang et al. (doi: 10.1016/j.jviromet.2021.114335), and used in 2 separate primer pools.
Amplicon size
500bp, 1000bp, 2000bp
Sequencing instrument
Illumina MiniSeq [OBI:0003114]
Sequencing protocol
Genomes were generated through amplicon sequencing of 500, 1000, and 2000 bp amplicons in separate primer pools. Libraries were created using KAPA HyperPrep Kit, and sequence data was produced using Illumina MiniSeq
Sequencing assay type
whole genome sequencing assay [OBI:0002117]
Reference genome accession
PP109421.1
Depth of coverage
7423
Breadth of coverage
99

Submission details

Submission ID
QKQYTLIHO0
Submitting group
Date submitted
2025-05-26 11:47:26 UTC
Date released
2025-05-26 11:49:33 UTC
Earliest release date
2025-05-26

Alignment and QC

Length
15204 (99.9%)
# of SNPs
121
# of deleted bases
2
# of unknown bases
5

Nucleotide mutations

Mutations called relative to the OP975389.1 reference

Substitutions

  • G1A
  • C3G
  • G513T
  • G579A
  • G787A
  • G1031A
  • G1385A
  • C1684T
  • G1732A
  • G1768A
  • C1792A
  • T1846C
  • C2074T
  • C2198T
  • A2367T
  • G2389A
  • T2418C
  • C2511T
Deletions

973, 4586
Insertions
N/A

Amino acid mutations

Mutations called relative to the OP975389.1 reference

Substitutions

F

  • F:K68N
  • F:S190N
  • F:S211N
  • F:S389P

G

  • G:A74V
  • G:S100G
  • G:T131A
  • G:I137T
  • G:P214S
  • G:P221L
  • G:P245S
  • G:I252T
  • G:I268T
  • G:S275P
  • G:Y285H
  • G:S295F

L

  • L:S169P
  • L:K322R
  • L:K570R
  • L:N839S
  • L:I1523V
  • L:R1759K
  • L:T1987I

M2-2

  • M2-2:I2T
  • M2-2:M27T
  • M2-2:D35N
  • M2-2:C49F

N

  • N:V97I

P

  • P:A29T
Deletions
N/A
Insertions
N/A

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